Description: Toll-Like Receptors by Francesca Fallarino, Marco Gargaro, Giorgia Manni This volume provides methods on the role of TLRs in immune responses and on the various approaches targeting different TLRs in cancer, autoimmunity and in vaccine development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Toll-Like Receptors: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. FORMAT Hardcover CONDITION Brand New Table of Contents Modelling of transmembrane domain and full length TLRs in membrane models.- Development of Optimal Virtual Screening Strategies to Identify Novel Toll-like Receptor Ligands using the DockBox Suite.- Use of Fluorescent Chemical Probes in the Study of Toll-like Receptors (TLRs) Trafficking.- Use of Fluorescent Chemical Probes in the Study of Toll-like Receptors (TLRs) Trafficking.- Endotoxin-tolerance mimicking to study TLR in promotion of tolerogenic DCs and Tr1 cells.- Flow cytometry analysis of IL-1 receptors and Toll like receptors on platelets and platelet-derived extracellular vesicles.- Methods to study TLRs in transplantation.- Determining endosomal Toll-like Receptors gene expression in NK cells after stimulation with specific agonists.- In vitro study of TLR4-NLRP3-inflammasome activation pathway in innate immune response.- Toll-like receptor polymorphisms and the risk of cancer: meta-analysis study.- Unrevealing the role of TLRs in the pathogenesis of autoimmune disease by using mouse model of diabetes.- In vitro and ex vivo methodologies for T cell trafficking through Blood Brain Barrier after TLR activation.- Delineating the role of Toll-like receptors in inflammatory bowel disease.- Analysis of differential TLR activation in a mouse model of multiple sclerosis.- Study of agonists of TLRs as vaccine adjuvants.- Activation of TLRs by opportunistic fungi in lung organoids. Details ISBN1071633651 Author Giorgia Manni Publisher Springer-Verlag New York Inc. Series Methods in Molecular Biology ISBN-13 9781071633656 Format Hardcover Imprint Springer-Verlag New York Inc. Subtitle Methods and Protocols Place of Publication New York, NY Country of Publication United States Edited by Giorgia Manni AU Release Date 2024-03-13 NZ Release Date 2024-03-13 UK Release Date 2024-03-13 Year 2023 Alternative 9781071633687 Series Number 2700 Audience Professional & Vocational DEWEY 572.696 Pages 286 Publication Date 2023-08-22 US Release Date 2023-08-22 Illustrations 42 Illustrations, color; 3 Illustrations, black and white; XI, 286 p. 45 illus., 42 illus. in color. ISBN-10 1071633651 Edition Description 2023 ed. Edition 2023rd We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:159861288;
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Author: Francesca Fallarino, Marco Gargaro, Giorgia Manni
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