Description: Targeted Genome Editing Using Site-Specific Nucleases Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). ZFNs, TALENs, and the CRISPR/Cas9 System Author(s): Takashi Yamamoto Format: Paperback Publisher: Springer Verlag, Japan, Japan Imprint: Springer Verlag, Japan ISBN-13: 9784431562351, 978-4431562351 Synopsis This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields.
Price: 116.32 GBP
Location: Aldershot
End Time: 2025-02-05T12:24:23.000Z
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Book Title: Targeted Genome Editing Using Site-Specific Nucleases
Number of Pages: 205 Pages
Publication Name: Targeted Genome Editing Using Site-Specific Nucleases: Zfns, Talens, and the Crispr/Cas9 System
Language: English
Publisher: Springer Verlag, Japan
Item Height: 235 mm
Subject: Zoology, Biology
Publication Year: 2016
Type: Textbook
Item Weight: 3736 g
Author: Takashi Yamamoto
Item Width: 155 mm
Format: Paperback