Stress & Developmental Programming of Health & Disease: Beyond Phenomenology by

Description: Stress & Developmental Programming of Health & Disease by Lubo Zhang, Lawrence D. Longo Estimated delivery 3-12 business days Format Hardcover Condition Brand New Description One of the most provocative recent findings in modern medicine is that perinatal stress may have a subtle or drastic impact on tissue/organ ontogeny, structure, and function, altering the vulnerability or resiliency to challenges and diseases later in life. A wealth of evidence indicates that stress and adverse environmental milieu during early development is closely associated with increased risks of the genesis of hypertension, coronary artery disease, insulin resistance, type 2 diabetes, central obesity, hyperlipidemia, and other neurobehavioral, neuropsychological and neuropsychiatric disorders in adulthood. The concept of "Developmental Programming of Health and Disease" or "Foetal Origins of Adult Disease" has been developed to elucidate the links between stress, early development, and risks of disease later in life. Stress is an internal response to stimuli or pressures that challenge or disrupt an organisms homeostasis in a changing environment. Adverse environmental signals that influence the development cause foetal stress.Such adverse signals can be transmitted from the mother to the foetus, impacting specific vulnerable tissues in their sensitive developmental stage, modulating normal development trajectory, remodelling their structure and function and reprogramming the resiliency or susceptibility to diseases in postnatal life. Such programming may be determined by multiple factors including gestational age, duration and mode of exposure and nature of the stressor, and these processes are tissue/organ specific. Genetic traits, epigenetic modifications and central stress mediators such as dopamine, glucocorticoids, and other transmitters may underpin such phenotypic plasticity. This volume provides broad and up-to-date information in the recent advancement of our knowledge in the basic science of Developmental Programming of Health and Disease.Each Chapter is written by leading experts in the field, providing the highest academic level for readers including basic, clinical, and translational scientists, paediatricians, maternal-foetal medicine specialists, physiologists, environmental biologists, biostatisticians, sociologists, behavioural scientists, health economists, health informatics experts, geneticists, microbiologists, epidemiologists, medical students, university undergraduate students, and graduate students. Details ISBN 1633218368 ISBN-13 9781633218369 Title Stress & Developmental Programming of Health & Disease Author Lubo Zhang, Lawrence D. Longo Format Hardcover Year 2014 Pages 685 Publisher Nova Science Publishers Inc GE_Item_ID:88775779; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys

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