Description: In 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a "most beautiful" experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic Holmes shows in this masterful account of Meselson and Stahl's quest. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research - its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl's research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community's reception of the experiment, the experiment's influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment.
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EAN: 9780300085402
UPC: 9780300085402
ISBN: 9780300085402
MPN: N/A
Item Length: 29.6 cm
Number of Pages: 528 Pages
Publication Name: Meselson, Stahl, and the Replication of D N A: a History of the Most Beautiful Experiment in Biology
Language: English
Publisher: Yale University Press
Item Height: 242 mm
Subject: Science, Biology
Publication Year: 2002
Type: Textbook
Item Weight: 944 g
Author: Frederic Lawrence Holmes
Item Width: 159 mm
Format: Hardcover
