Description: Mechanisms of Lymphocyte Activation and Immune Regulation III by Sudhir Gupta, William E. Paul, Max D. Cooper, Ellen V. Rothenberg Estimated delivery 3-12 business days Format Paperback Condition Brand New Description In parallel, there has been considerable progress in our understanding of tolerance, based in part on the use of markers for the V fJ genes of T-cell receptors and in part on the analysis of the behavior of long term T-cell lines. Publisher Description Recent advances in the understanding of the major events that shape the immune recog nition system have been remarkable. The analysis of immunoglobulin (Ig) gene organization and Ig repertoire diversification in lower vertebrates has provided new insight into this process in mammals. Similarly, the understanding of the early development of lymphocytes and of the acquisition of immunological tolerance has been aided by elegant studies in quail/chicken chimeras, using the power of the distinctive markers of the constitutive cells of these birds. Great strides have been made in understanding the role played by major histocompatibility complex (MHC) molecules in antigen presentation and in repertoire selec tion within the thymus. The use of transgenic mice expressing specific T-cell receptor (TCR) genes has elucidated the process of both positive and negative selection. In parallel, there has been considerable progress in our understanding of tolerance, based in part on the use of markers for the V fJ genes of T-cell receptors and in part on the analysis of the behavior of long term T-cell lines. This has led to the realization that both clonal deletion and clonal anergy may play critical roles in the maintenance of unresponsiveness to self antigen. Molecular analysis of the requirements for expression of membrane immunoglobulin molecules has revealed the existence of a complex that appears to be of critical importance in mediating signalling through Ig receptors. In addition, major insights have been obtained into the regulation of expression of genes of immunologic interest. Details ISBN 1468459457 ISBN-13 9781468459456 Title Mechanisms of Lymphocyte Activation and Immune Regulation III Author Sudhir Gupta, William E. Paul, Max D. Cooper, Ellen V. Rothenberg Format Paperback Year 2012 Pages 268 Publisher Springer-Verlag New York Inc. GE_Item_ID:158861697; About Us Grand Eagle Retail is the ideal place for all your shopping needs! With fast shipping, low prices, friendly service and over 1,000,000 in stock items - you're bound to find what you want, at a price you'll love! Shipping & Delivery Times Shipping is FREE to any address in USA. Please view eBay estimated delivery times at the top of the listing. Deliveries are made by either USPS or Courier. We are unable to deliver faster than stated. International deliveries will take 1-6 weeks. NOTE: We are unable to offer combined shipping for multiple items purchased. This is because our items are shipped from different locations. Returns If you wish to return an item, please consult our Returns Policy as below: Please contact Customer Services and request "Return Authorisation" before you send your item back to us. Unauthorised returns will not be accepted. Returns must be postmarked within 4 business days of authorisation and must be in resellable condition. Returns are shipped at the customer's risk. We cannot take responsibility for items which are lost or damaged in transit. For purchases where a shipping charge was paid, there will be no refund of the original shipping charge. Additional Questions If you have any questions please feel free to Contact Us. Categories Baby Books Electronics Fashion Games Health & Beauty Home, Garden & Pets Movies Music Sports & Outdoors Toys
Price: 67.04 USD
Location: Fairfield, Ohio
End Time: 2025-01-22T03:46:18.000Z
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Restocking Fee: No
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ISBN-13: 9781468459456
Book Title: Mechanisms of Lymphocyte Activation and Immune Regulation III
Number of Pages: 268 Pages
Language: English
Publication Name: Mechanisms of Lymphocyte Activation and Immune Regulation III : Developmental Biology of Lymphocytes
Publisher: Springer
Item Height: 0.2 in
Publication Year: 2012
Subject: Immunology, Life Sciences / Anatomy & Physiology (See Also Life Sciences / Human Anatomy & Physiology), Life Sciences / Zoology / General
Type: Textbook
Item Weight: 18.4 Oz
Subject Area: Science, Medical
Item Length: 10 in
Author: William E. Paul
Series: Advances in Experimental Medicine and Biology Ser.
Item Width: 7 in
Format: Trade Paperback
