Description: Matrix Metalloproteinases in Health and Disease by Raffaele Serra Matrix metalloproteinases (MMPs) are members of an enzyme family and are critical for maintaining tissue allostasis. MMPs can catalyze normal turnover of the extracellular matrix (ECM) together with other metalloproteinases such as ADAM (a disintegrin and metalloproteinase) and ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) families. MMP activity is also regulated by a group of endogenous proteins called tissue inhibitor of metalloproteinases (TIMPs). All these proteins have a pivotal role involving ECM remodelling in normal physiological processes such as wound healing, embryogenesis, angiogenesis, bone remodelling, immunity, and the female reproductive cycle. An imbalance in the expression or activity of MMPs can also have important consequences in diseases such as cancer, cardiovascular disease, peripheral vascular disease, chronic leg ulcers, and multiple sclerosis. In recent years, MMPs have been found to play an important role in the field of precision medicine, as they may serve as biomarkers that may predict an individuals disease predisposition, state, or progression. MMPs are also thought to be a sensible target for molecular therapy. The aim of this Special Issue is to explore the most recent findings in this field that may have an impact in healthcare systems. FORMAT Hardcover CONDITION Brand New Details ISBN3039430521 Pages 196 Year 2020 ISBN-10 3039430521 ISBN-13 9783039430529 Format Hardcover Publication Date 2020-09-11 UK Release Date 2020-09-11 Imprint Mdpi AG Author Raffaele Serra Publisher Mdpi AG Audience General We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:129860907;
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Format: Hardcover
ISBN-13: 9783039430529
Author: Raffaele Serra
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Book Title: Matrix Metalloproteinases in Health and Disease
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