Description: Matrix Metalloproteinase Inhibitors : Specificity of Binding and Structure-Activity Relationships, Hardcover by Gupta, Satya Prakash (EDT), ISBN 303480363X, ISBN-13 9783034803632, Like New Used, Free P&P in the UK
Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth andmetastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases.
The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development.
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Book Title: Matrix Metalloproteinase Inhibitors : Specificity of Binding and
Number of Pages: 286 Pages
Language: English
Publication Name: Matrix Metalloproteinase Inhibitors: Specificity of Binding and Structure-Activity Relationships
Publisher: Springer Basel
Publication Year: 2012
Subject: Biology
Item Height: 235 mm
Item Weight: 612 g
Type: Textbook
Author: Satya Prakash Gupta
Series: Experientia Supplementum
Item Width: 155 mm
Format: Hardcover
