Description: This book introduces readers to the biology of leukemia stem cells (LSCs) and emphasizes the necessity and importance of targeting LSCs in the treatment of hematopoietic malignancies. It addresses the role of leukemia stem cells in different leukemia diseases and molecular signatures, as well as the metabolic and epigenetic regulation of leukemia stem cell function. With regard to solid tumors, a significant number of blood cancers are believed to be derived from leukemia stem cells (LSCs), which are responsible for disease progression, relapse and drug resistance. Consequently, new therapeutic strategies need to be developed by focusing on the complete eradication of LSCs. Given its scope, the book offers a valuable asset for graduate students and scientists in the fields of cell biology and cancer research etc.
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EAN: 9789811373411
UPC: 9789811373411
ISBN: 9789811373411
MPN: N/A
Recommended Age Range: 0-12 months
Item Length: 23.4 cm
Number of Pages: 229 Pages
Publication Name: Leukemia Stem Cells in Hematologic Malignancies
Language: English
Publisher: Springer Verlag, Singapore
Item Height: 235 mm
Subject: Medicine, Biology
Publication Year: 2019
Type: Textbook
Item Weight: 530 g
Author: Shaoguang Li, Haojian Zhang
Item Width: 155 mm
Format: Hardcover