Description: About this Item The item is a book Paperback The Author Name is John C. Lucchesi The Title is Epigenetics, Nuclear Organization & Gene Function : With implications of epigenetic regulation and genetic architecture for human development and health Condition New Other Comments Pages Count - 306. Binding type - Perfect. Content Language - English Category - SCIENCE / Life Sciences / Genetics & Genomics SCIENCE / Life Sciences / Biochemistry Product Description - Epigenetics is the study of heritable changes in gene function that do not involve changes in the DNA sequence. These changes, consisting principally of DNA methylation, histone modifications, and non-coding RNAs, maintain or modulate the initial impact of regulatory factors that recognize and associate with particular genomic sequences. Epigenetic modifications are manifest in all aspects of normal cellular differentiation and function, but they can also havedamaging effects that result in pathologies such as cancer. Research is continuously uncovering the role of epigenetics in a variety of human disorders, providing new avenues for therapeutic interventions and advances in regenerative medicine. This book's primary goal is to establish a framework that can be used to understand the basis of epigenetic regulation and to appreciate both its derivation from genetics and interdependence with genetic mechanisms. A further aim is to highlight the role played by the three-dimensional organization of the genetic material itself the complex of DNA, histones and non-histone proteins referred to as chromatin, and its distribution within a functionally compartmentalized nucleus. Thisarchitectural organization of the genome plays a major role in the subsequent retrieval, interpretation, and execution of both genetic and epigenetic information. We Use Stock Images Because we have over 2 million items for sale we have to use stock images, this listing does not include the actual image of the item for sale. The purchase of this specific item is made with the understanding that the image shown in this listing is a stock image and not the actual item for sale. For example: some of our stock images include stickers, labels, price tags, hyper stickers, obi's, promotional messages, signatures and or writing which may not be available in the actual item. When possible we will add details of the items we are selling to help buyers know what is included in the item for sale. The details  are provided automatically  from our central master database and can sometimes be wrong. Books are released in many editions and variations, such as standard edition, re-issue, not for sale, promotional, special edition, limited edition, and many other editions and versions.  The Book you receive could be any of these editions or variations. If you are looking for a specific edition or version please contact us to verify what we are selling.   Gift IdeasThis is a  great Christmas gift idea.   Hours of ServiceWe have many warehouses,  some of the warehouses process orders seven days a week, but the Administration Support Staff are located at a head office location, outside of the warehouses, and typically work only Monday to Friday. Location ID 555z iHaveit SKU ID 163698682
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Location: GB
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Fiction/Non-Fiction: Non-Fiction
Genre/Subject: SCIENCE / Life Sciences / Genetics Genomics
Brand: Oxford University Press
Weight: 0.55
Style: NA
Title: Epigenetics Nuclear Organization Gene Function With implicat
Release Title: Epigenetics Nuclear Organization Gene Function With implicat
Record Grading: New
Sleeve Grading: New
Platform: NA
Size: NA
Film/TV Title: Epigenetics Nuclear Organization Gene Function With implica
Colour: NA
Material: NA
Department: NA
Binding Type: Perfect
Item Length: 246.13
Main Stone: NA
Metal Purity: NA
Metal: NA
Connectivity: NA
Model: NA
Number of Pages: 304 Pages
Language: English
Publication Name: Epigenetics, Nuclear Organization & Gene Function: With implications of epigenetic regulation and genetic architecture for human development and health
Publisher: Oxford University Press
Publication Year: 2019
Subject: Biology
Item Height: 247 mm
Item Weight: 634 g
Type: Textbook
Author: John C. Lucchesi
Item Width: 190 mm
Format: Paperback