Description: Human Epigenetics: How Science Works Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Carsten Carlberg, Ferdinand Molnar Format: Paperback Publisher: Springer Nature Switzerland AG, Switzerland Imprint: Springer Nature Switzerland AG ISBN-13: 9783030229061, 978-3030229061 Synopsis The view "It's all in our genes and we cannot change it" developed in the past 150 years since Gregor Mendel's experiments with flowering pea plants. However, there is a special form of genetics, referred to as epigenetics, which does not involve any change of our genes but regulates how and when they are used. In the cell nucleus our genes are packed into chromatin, which is a complex of histone proteins and genomic DNA, representing the molecular basis of epigenetics. Our environment and lifestyle decisions influence the epigenetics of our cells and organs, [url] epigenetics changes dynamically throughout our whole life. Thus, we have the chance to change our epigenetics in a positive as well as negative way and present the onset of diseases, such a type 2 diabetes or cancer. This textbook provides a molecular explanation how our genome is connected with environmental signals. It outlines that epigenetic programming is a learning process that results in epigenetic memory in each of the cells of our body. The central importance of epigenetics during embryogenesis and cellular differentiation as well as in the process of aging and the risk for the development of cancer are discussed. Moreover, the role of the epigenome as a molecular storage of cellular events not only in the brain but also in metabolic organs and in the immune system is described. The book represents an updated but simplified version of our textbook "Human Epigenomics" (ISBN [tel]. The first five chapters explain the molecular basis of epigenetics, while the following seven chapters provide examples for the impact of epigenetics in human health and disease.
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Location: Aldershot
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Book Title: Human Epigenetics: How Science Works
Item Height: 235 mm
Item Width: 155 mm
Author: Ferdinand Molnar, Carsten Carlberg
Publication Name: Human Epigenetics: How Science Works
Format: Paperback
Language: English
Publisher: Springer Nature Switzerland A&G
Subject: Biology
Publication Year: 2019
Type: Textbook
Item Weight: 369 g
Number of Pages: 153 Pages