Description: Dt Cell Cancer Immunotherapy : Evidence-based Perspectives for Clinical Translation, Hardcover by Barisa, Marta (EDT), ISBN 0443217661, ISBN-13 9780443217661, Brand New, Free shipping in the US ?d T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation sets out and critically discusses the current clinical and relevant preclinical ?d T cell immunotherapy landscape. In five chapters, field experts discuss the challenges facing ?d T cell oncoimmunotherapy, propose solutions, and map next steps. Particular attention is given to summarizing our understanding of the complex, translationally relevant human ?d T cell biology, the evidence basis for designing ?d T cell combination trials and data-driven perspectives on what is known—and what isn’t—about ?d T cell therapeutic persistence. Various perspectives are provided on how issues of cytotoxic effector function, functional exhaustion, and cytokine addiction can be mitigated using gene engineering. A chapter is dedicated to the systematic review of all ?d T cell immunotherapy trials to date, and the cell therapy products that were used in these trials. The final chapter discusses allograft persistence-enhancement techniques in the context of ?d T cell therapy, covering lymphodepleting chemotherapy and synthetic stealth engineering. ?d T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation gives an updated and comprehensive insight into the current state of ?dT cell immunotherapy, which is of interest to existing translational ?d T cell specialists, the proliferating range of academic scientists and commercial scientists entering the field, as well as clinicians who may encounter ?d T cell immunotherapy in the clinic, or are wishing to familiarize themselves with noncanonical lymphocyte immunotherapy.
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Book Title: Dt Cell Cancer Immunotherapy : Evidence-based Perspectives for Cl
Number of Pages: 286 Pages
Language: English
Publication Name: ΓΔ T Cell Cancer Immunotherapy : Evidence-Based Perspectives for Clinical Translation
Publisher: Elsevier Science & Technology
Publication Year: 2024
Subject: Life Sciences / General, Internal Medicine, Life Sciences / Biology
Type: Textbook
Subject Area: Science, Medical
Item Length: 9.2 in
Author: Marta Barisa
Item Width: 7.5 in
Series: Breaking Tolerance to Anti-Cancer Cell-Mediated Immunotherapy Ser.
Format: Hardcover
