DNA Methylation: Development, Genetic Disease and Cancer by Walter Doerfler (Eng

Description: DNA Methylation: Development, Genetic Disease and Cancer by Walter Doerfler, Petra Böhm It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems. Back Cover (Back cover text will follow) Table of Contents The Regulation of Chromatin and DNA-Methylation Patterns in Blood Cell Development.- Methylation Dynamics in the Early Mammalian Embryo: Implications of Genome Reprogramming Defects for Development.- Epigenetic Regulation in Drosophila.- Epimutations in Human Disease.- Epigenotypes of Latent Herpesvirus Genomes.- Epigenetics of Complex Diseases: From General Theory to Laboratory Experiments.- MSL Proteins and the Regulation of Gene Expression.- DNA Methylation Profiles of Female Steroid Hormone-Driven Human Malignancies.- Genome-wide Analysis of DNA Methylation Changes in Human Malignancies.- Decreased Fidelity in Replicating DNA Methylation Patterns in Cancer Cells Leads to Dense Methylation of a CpG Island.- Methylation of Endogenous Human Retroelements in Health and Disease.- Cancer-Linked DNA Hypomethylation and Its Relationship to Hypermethylation. Long Description It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems. Feature Includes supplementary material: sn.pub/extras Details ISBN3540311807 Author Petra Böhm Language English ISBN-10 3540311807 ISBN-13 9783540311805 Media Book Format Hardcover Year 2006 Imprint Springer-Verlag Berlin and Heidelberg GmbH & Co. K Subtitle Development, Genetic Disease and Cancer Place of Publication Berlin Country of Publication Germany DEWEY 572.86 Series Number 310 Short Title DNA METHYLATION DEVELOPMENT GE Birth 1933 Affiliation Institut f. Genetik, Univ. zu Koln, Weyertal 121, 50931 Kol Pages 284 DOI 10.1604/9783540311805;10.1007/3-540-31181-5;10.1007/978-3-540-31181-2 UK Release Date 2006-06-22 Publisher Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Edition Description 2006 ed. Series Current Topics in Microbiology and Immunology Edition 2006th Publication Date 2006-06-22 Alternative 9783642068300 Edited by Petra Böhm Audience Professional & Vocational Illustrations IX, 284 p. We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:96309576;

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