Coronavirus Drug Discovery: Volume 3: Druggable Targets and In Silico Update by

Description: Coronavirus Drug Discovery by Chukwuebuka Egbuna Coronavirus Drug Discovery, Volume Three: Druggable Targets and In Silico Update presents comprehensive information on drug discovery against COVID-19. Chapters in Part One of this volume describe the various druggable targets and associated signaling pathways for effective targeting of SARS-CoV-2. In Part Two, chapters discuss the various computational approaches and in silico studies against SARS-CoV-2. Written by global team of experts, this book is an excellent resource that will be extremely useful to drug developers, medicinal chemists, pharmaceutical companies in R&D, research institutes in both academia and industry, and the National Library of Medicines and Health.In addition, agencies such as the National Institutes of Health, Centers for Disease Control and Prevention, World Health Organization, European Medicines Agency, the US Food and Drug Administration, and all others involved in drug discovery against COVID-19 will find this book useful. FORMAT Paperback LANGUAGE English CONDITION Brand New Author Biography Chukwuebuka Egbuna (PhD) is a chartered chemist and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Royal Society of Chemistry (RSC) (United Kingdom). Dr. Egbuna is the founder and editor of the Elsevier book series on Drug Discovery Update. The series includes books, monographs, and edited collections from all areas of drug discovery including emerging therapeutic claims for the treatment of diseases. He has published research articles in many international journals of repute and is ranked among the top 500 Nigerian scientists in SciVal/SCOPUS. He has edited more than 25 books with Elsevier, Springer, Wiley, and Taylor & Francis. His most recent book is the three volume Coronavirus Drug Discovery, published by Elsevier. Dr. Egbuna is the founder and the publishing director of IPS Intelligentsia Publishing Services. Table of Contents PART 1: DRUGGABLE TARGETS AND SIGNALING PATHWAYS 1. SARS-CoV-2 genome sequencing and promising druggable targets 2. Signaling pathways implicated in SARS-CoV2 infection 3. Roles of membrane lipids and lipid synthesis inhibitors in the propagation of coronavirus disease 4. Potential Drugs in SARS-CoV-2 Treatment: Key Features and Mechanisms of ActionsPART 2: COMPUTATIONAL APPROACHES 5. Application of computational tools for coronavirus drug discovery 6. In silico Approaches in Drug Discovery for SARS-CoV-2 7. Application of molecular docking and dynamics tools in SARS-CoV-2 drug design: Ligand-protein interaction studies 8. Molecular dynamic simulation with protein and detection of repurposable drugs for COVID-19 9. Computation-guided inhibitor screening against the nucelocapsid of SARS-CoV-2 10. In-silico insight into the interaction of 4-aminoquinolines with selected SARS-CoV-2 structural and non-structural proteins 11. In silico Evaluation of Anti-SARS-CoV-2 Activity of Punica granatum L. Phytochemicals 12. In silico Investigation and Identification of Bioactive Compounds from Medicinal Plants as Potential Inhibitors against SARS-CoV-2 Cellular Entry Feature Discusses the pathogenic mechanisms of SARS-CoV-2 and druggable targets Reviews the various signaling pathways associated with SAR-CoV-2 as possible druggable targets Presents computational approaches and in silico studies against SARS-CoV-2 Details ISBN0323955789 Series Drug Discovery Update Language English Year 2022 ISBN-10 0323955789 ISBN-13 9780323955782 Format Paperback Publisher Elsevier - Health Sciences Division Imprint Elsevier - Health Sciences Division Place of Publication Philadelphia Country of Publication United States Pages 406 Publication Date 2022-07-12 US Release Date 2022-07-12 UK Release Date 2022-07-12 Author Chukwuebuka Egbuna Subtitle Volume 3: Druggable Targets and In Silico Update Edited by Chukwuebuka Egbuna Alternative 9780323955799 DEWEY 616.2414 Audience Professional & Vocational NZ Release Date 2022-07-11 AU Release Date 2022-07-11 We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:135537011;

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