An Introduction to Toxicogenomics by Michael E. Burczynski (English) Hardcover B

Description: An Introduction to Toxicogenomics by Michael E. Burczynski With a focus on toxicology, this text introduces the overall concept underlying microarray/oligonucleotide array-based genomic analysis and how it fits into the field of biomedical research. It also includes the basics of data analysis and clustering methods. FORMAT Hardcover LANGUAGE English CONDITION Brand New Publisher Description Since the advent of cDNA microarrays, oligonucleotide array technology, and gene chip analysis, genomics has revolutionized the entire field of biomedical research. A byproduct of this revolution, toxicogenomics is a fast-rising star within toxicological analysis. Gathering together leading authors and scientists at the forefront of the field, An Introduction to Toxicogenomics provides a comprehensive overview of this new discipline. With a focus on toxicology, it introduces the basic principles of microarray/oligonucleotide array-based genomic analysis and explains how it fits into the field of biomedical research. These discussions provide an overview to the actual mechanics of the analyses themselves and offer insights on handling and quality control. Then the book features an important section on the basics of data analysis and clustering methods such as genetic algorithms. Finally, it covers the application of expression profiling in the field of toxicology and addresses the two fundamental types of analysis in detail, with sections dedicated to both mechanistic and predictive studies.A lthough toxicogenomics promises fast, efficient techniques and information-rich data, much of its potential remains untapped.An Introduction to Toxicogenomics consolidates the concepts underlying the field to provide a solid foundation from which to begin your research endeavors. Author Biography Michael E. Burczynski Table of Contents Fundamentals of Expression Profiling Analysis. Expression Profiling and Toxicology: The Advent of Toxicogenomics. Model Systems in Toxicogenomic Studies. Mechanistic Toxicogenomics. Predictive Toxicogenomics. The Future of Toxicogenomics. Review "… Burczynski has carefully constructed this volume to encompass background information and basic science through to applications and future uses. … [This book] takes a complex, nascent science, reducing its complexity to details and discussions at the level of the … readership." - Veterinary Pathology, 42:1, 2005 "…a great text that explains the concepts underlying this new field to readers who will use these approaches in future research. It provides a comprehensive overview of this new discipline by focusing on toxicology. Its a good and needed guide to get into toxicogenomics in the right productive and accurate way." - in Vet Human ToxicologyPromo Copy Review Quote "... Burczynski has carefully constructed this volume to encompass background information and basic science through to applications and future uses. ... [This book] takes a complex, nascent science, reducing its complexity to details and discussions at the level of the ... readership." - Veterinary Pathology, 42:1, 2005 "...a great text that explains the concepts underlying this new field to readers who will use these approaches in future research. It provides a comprehensive overview of this new discipline by focusing on toxicology. Its a good and needed guide to get into toxicogenomics in the right productive and accurate way." - in Vet Human Toxicology Promo Copy Details ISBN0849313341 Author Michael E. Burczynski Short Title INTRO TO TOXICOGENOMICS Language English ISBN-10 0849313341 ISBN-13 9780849313349 Media Book Format Hardcover DEWEY 616.042 Year 2003 Imprint CRC Press Inc Country of Publication United States Edition 1st Edited by Michael E. Burczynski Place of Publication Bosa Roca Affiliation Biomarker Laboratory, Collegeville, PA, USA DOI 10.1604/9780849313349 UK Release Date 2003-03-26 AU Release Date 2003-03-26 NZ Release Date 2003-03-26 US Release Date 2003-03-26 Pages 356 Publisher Taylor & Francis Inc Publication Date 2003-03-26 Alternative 9780367395308 Illustrations 47 Tables, black and white; 59 Halftones, black and white; 6 Illustrations, color; 107 Illustrations, black and white Audience General We've got this At The Nile, if you're looking for it, we've got it. With fast shipping, low prices, friendly service and well over a million items - you're bound to find what you want, at a price you'll love! TheNile_Item_ID:134448330;

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